locus

BSU25430

BSU_25430

outlinks

bsu

BSU25430

BSU_25430

The protein

Catalyzed reaction/ biological activity

modification of N(6)-threonylcarbamoyladenosine (t(6)A) to 2-methylthio-N(6)-threonylcarbamoyladenosine (ms(2)t(6)A) in tRNA [Pubmed|27913733,20472640]

[sulfur carrier]-SH + AH₂ + N⁶-L-threonylcarbamoyladenosine³⁷ in tRNA + 2 S-adenosyl-L-methionine --> 2-methylsulfanyl-N⁶-L-threonylcarbamoyladenosine³⁷ in tRNA + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H⁺ + L-methionine + S-adenosyl-L-homocysteine (according to UniProt)

The protein

Protein family

YqeV subfamily (according to Swiss-Prot)

methylthiotransferase family (with [[protein|YmcB]], according to UniProt)

The protein

[SW|Domains]

MTTase N-terminal domain (aa 2-114) (according to UniProt)

[SW|TRAM domain] (aa 372-437) (according to UniProt)